Fathi Halaweish Research

Research Summary

My group conducts research on the structural, synthetic and medicinal chemistry of natural products, as well as optimization of analogs derived from natural products. This includes molecular modeling, molecular dynamics, chemical and biological investigation and methods development for drug discovery of exceedingly small amounts of rare natural products using NMR, mass spectrometry (MS) and synthesis of drug-like analogs for therapeutic areas using in silico approaches.

We have developed several drug candidates and expertise in Hit-to-Lead optimization (computational support and/or synthetic medicinal chemistry output) utilizing library analysis, analogue design and allosteric site identification.